Withdrawing from Stocks and Shares Isa UK

I have two Stocks and Shares ISAs. One opened in 2020, and one opened in 2022.. As I have been depositing money into the 2022 ISA, I've not touched the 2020 one. Can I still withdraw money from the 2020 one?

I am aware that I can't input any money into the 2020 one but no one mentions withdrawal. Will I be taxed/penalised?

Thanks!