Advice needed on how to deal with stocks that have been in the minus for a while

Genuinely looking for advice if my thinking is correct or if I'm being too impatient.

I have a few stocks which I've held on to stubbornly despite them falling more each passing month.

Namely: $YSN $BNTX $PYPL $BABA $JD

I'm now thinking of taking a loss on YSN and BNTX and reinvest into an MSCI World index ETF. The rest might as well wait and see… would be -20% at least for each though which hurts when adding up.

What would you do? I appreciate your feedback!